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It was reported that [60] the overexpression of tTG in human neuroblastoma cells increases apoptosis

In addition, the sidechains of V40 and M44 from the center of ACP 2-helix form hydrophobic interactions with the sidechains of FabX I156 and K159 which further stabilize ACPFabX binding

Due to its significant potential for cognitive improvement and neuroregenerative capacity, this compound has received widespread attention in neuroscience and drug development in recent years
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