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4 , 5 The pain reducing effects of acute treatments with vitamin B 12 alone or in combination with other B vitamins including vitamins B 1 and B 6 have been reported in sciatic nerve crush, spinal nerve ligature and diabetic models of neuropathic pain in rats and mice

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In neuropathic conditions, methylcobalamin supports nerve regeneration and can help reduce symptoms such as pain, tingling, and numbness

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