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Undeniably, the brain is highly susceptible to ROS-induced oxidative damage, as a result of the existence of high amounts of polyunsaturated fatty acids and oxygen, due to the high oxygen consumption rate, thereby acting as a substrate for lipid peroxidation (Cobley et al

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Curr Protein Pept Sci 20:907917 Shi Y, Wu W, Yang Y, Liu X, Lin J, Liu X (2023) Gene knockout of glutathione reductase results in increased sensitivity to heavy metals in Acidithiobacillus caldus

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