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2 Sun, Xiaojin, et al

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The Food and Drug Administration has recommended that a person with chronic kidney disease who has a low Hgb, most likely has anemia caused by decreased EPO production
B12 supplementation in people who are not deficient does not produce meaningful additional energy benefits beyond what normal B12 levels already provide

The rate was highest in the first month of treatment

10.2174/1381612824666180608101119 18 SikiricP.SeiwerthS.GrabarevicZ.RucmanR.PetekM.RotkvIcI.et al (1993)
