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In the end, a sample population of 121 patients (63 male, 58 female) were included in the study, adding up to n = 9680 tooth surfaces, the largest amount of tooth sufaces reported in literature 2,10,11,12,18,24,29,30,31,32,33

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2 (download XLSX Numerical source data

During times of stress, such as sleep disruption and even aging itself, these challenges can cause the levels of brain creatine to decrease [7]

Interestingly, we also observed a significant increase in FPI in these elderly patients