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Colla, R., Izzotti, A., De Ciucis, C., Fenoglio, D., Ravera, S., Speciale, A
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A., and Mortensen, R

Tong Ki, Padmanabhan B, Kobayashi A, et al

Moreover, all clinical trials are evolving, presenting progressively more complex designs, and this also renders first-in-human clinical trial design more complex and challenging
