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Polymeric drug delivery systems (PDDS) offer transformative potential for gout and hyperuricemia through controlled release, targeted delivery, and multi-mechanistic synergies

[DOI] [PubMed] [Google Scholar] 5.Owen O.E., Morgan A.P., Kemp H.G., Sullivan J.M., Herrera M.G., Cahill G.F

14 However, HIV-2 has a lower viral load, 14-16 is less pathogenic, 15,16 generally progresses more slowly than HIV-1, 16,17 and is mostly confined to West Africa

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36-38 when fully metabolized)

In addition, in rat endplate chondrocytes, the intervention of IGF-1 up-regulated the expression of MMP-13 through the ERK pathway, thereby inhibiting the decomposition of cartilage [30]