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doi: 10.1038/jid.2014.400

Furthermore, G6PDX hearts do not recover as well as nondeficient mice when faced with ischemia-reperfusion injury, and G6PDX mice are susceptible to the development of age-associated cardiac hypertrophy

[DOI] [PubMed] [Google Scholar] 196.Zheng L, Nukuna B, Brennan ML, Sun M, Goormastic M, Settle M, Schmitt D, Fu X, Thomson L, Fox PL, Ischiropoulos H, Smith JD, Kinter M and Hazen SL

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The concentrations of thiols in vivo are likely to contain a variable mixture of oxidized and reduced glutathione, cysteine, cystine, and proteins

Betaine serves as an osmolyte and methyl group donor, playing a role in the re-methylation of homocysteine into methionine, a precursor of S-adenosylmethionine (SAM), essential for numerous methylation reactions, including DNA epigenetics (2124)