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PINK1 mutations disturb kinase functions and neuroprotection

In clinical wound-care settings, adjunct topical GHK-Cu gels were associated with larger median reductions in ulcer area and fewer recorded wound infections relative to standard care alone, particularly in larger plantar lesions that were slower to progress under routine protocols

-synuclein E46K mutation was also identified to result in oxidative stress accumulation in SN DA neurons, likely increasing neuronal vulnerability towards mitochondrial impairment by mitochondrial toxins 152

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A 20 g dose without treatment is considered possibly lethal [38]