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Health economic evaluations of nonpharmacological interventions for persons with dementia and their informal caregivers: A systematic review

Although normal electron transport in mitochondria involves four-electron reduction of O 2 to water, partial reduction reactions occur under physiological conditions, causing release of superoxide anion and hydrogen peroxide (H 2 O 2 )

Though experimental studies of acute stress effects in humans are challenging, lab-based stressors such as the Trier Social Stress Test (TSST) have been used to demonstrate acute epigenetic changes

[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Johnson LK, Holven KB, Nordstrand N, Mellembakken JR, Tanbo T, Hjelmesth J

In another study, glioblastoma cell lines that had higher xanthine and hypoxanthine levels were more likely to develop radiotherapy resistance when compared to cell lines with lower xanthine levels [66]