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2 Epidemiological studies have historically estimated the prevalence of obstructive sleep apnea to be around 3% to 7% in men and 2% to 5% in women, but it is believed to be vastly underdiagnosed

Importantly, such dual-site immune cell infiltration has not been confirmed in human studies and should therefore be interpreted as preclinical evidence

Three short-term trials showed positive effects of omega-3 supplementation on plasma biochemical parameters (e.g., reduced inflammatory cytokine expression, increased plasma EPA and DHA concentrations) compared to controls (161)

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(A) Exemplar images of DAPI and SRB co-staining in control (CON), PRO (4.7 mM) and PE