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O 2 can reduce ferric iron (Fe 3+ ) to Fe 2+ , which suggests that it can play two roles in producing OH

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These, for example, include prodrug strategies, as seen in the case of OTC, which was designed to have improved bioavailability and stability (it is thought of being converted to cysteine intracellularly, which is then used for GSH synthesis) or NAC amide that has improved lipophilicity and cell permeability

10.3389/fphar.2019.01105 72 LethabyA.VollenhovenB