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535,536 Second-generation proteasome inhibitors, including carfilzomib, marizomib, and ixazomib, which may overcome the resistance and toxicity of bortezomib, are being evaluated in clinical investigations for myeloma bone disease, chronic lymphocytic lymphoma, and multiple myeloma
An evaluation in 78 PD patients and 32 controls showed considerably lower CSF t- -Syn levels in PD patients (Mollenhauer et al., 2019)
Among CagriSema-treated participants, 73.5% achieved HbA1c of 6.5% or below compared to 15.9% with placebo, demonstrating remarkable dual efficacy for both weight and glycemic endpoints
In: Singh AD, Damato B, eds
Schaefer, P
10.1136/bmj-2024-080133 25 CrumpJ.SukerA.WhiteL
