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Here, we update and discuss current rationale, evidence, and dosing guidelines for mitochondrial medicine therapies in patients with PMD including practical considerations as to which therapies may be administered parenterally and which genetic etiologies and/or phenotypes might be particularly responsive to specific therapies[25]

L cysteine vs NAC comparative investigations utilizing advanced proteomics and metabolomics technologies reveal distinct cellular uptake patterns and intracellular distribution profiles that influence therapeutic outcomes in different tissue types

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Sep 2016;33(9):1223-30

Collin, R.A