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Interestingly, this threshold was shifted to the left by 20-fold (0.025 mM) in GSH-deficient cells

Malik JA, Goel S, Sandhir R, Nayyar H (2011) Uptake and distribution of arsenic in chickpea: effects on seed yield and seed composition

Compared to the low concentrations of iAsIII (less than 1 M) in the blood of APL patients, MMAIII and DMAIII can generate reactive oxygen species (ROS) by targeting the mitochondria and endoplasmic reticulum (Ramachandran and Jaeschke, 2018) and activate autophagy, apoptosis, ferroptosis, inflammatory, fibrosis and necroptosis pathways (Figure 2 shows how arsenic exposure damages the liver

Inappropriate dosing recommendations on product labels can lead to ineffective supplementation or adverse reactions

The Lewy body formation and neuronal damage altogether enhance neurodegeneration

Kikuchi E, Margulis V, Karakiewicz PI, Roscigno M, Mikami S, Lotan Y, et al