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Most studies did not state whether the laboratory was blinded

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A direct relationship has been detected between the levels of Vitamin E in seminal plasma and the percentage of motile spermatozoa in semen.[37] Furthermore, lower levels of Vitamin E were observed in the semen of infertile men.[38] In contrast to earlier studies demonstrating no benefit from vitamin E supplementation in the treatment of male infertility,[39,40] recent placebo-controlled studies have suggested a favorable outcome

doi: 10.1007/s13311-016-0433-7

Data availability The authors declare that the data generated in this study are provided in the Supplementary Information and Source Data file

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