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Assay for oxidative burst Oxidative burst was measured by stimulation-induced oxygen consumption rate (OCR) using a XF-96e extracellular flux analyser (Agilent) following a protocol developed by Seahorse 71

This lactylation process, catalyzed by writer proteins like acetyltransferase p300, and reversible by eraser proteins such as histone deacetylases (HDACs), reveals lactates role as an epigenetic regulator and intercellular communicator [15]

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