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[DOI] [PubMed] [Google Scholar] 113.Pasquini L., Napolitano A., Tagliente E., Dellepiane F., Lucignani M., Vidiri A., Ranazzi G., Stoppacciaro A., Moltoni G., Nicolai M., et al

Cytokines such as IL-1 and TNF-, which are pivotal in inflammation, also serve as sleep-regulating molecules, promoting NREM sleep at physiological levels but contributing to sleep fragmentation when chronically elevated (Zielinski and Gibbons, 2022)