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Ionizing radiation can directly impair deoxyribonucleic acid (DNA), such as by inducing base deletions, DNA single-strand breaks (SSBs), and DNA double-strand breaks (DSBs) [31]

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Given that ASK neurons are essential for ascaroside pheromone-triggered behaviours and dauer formation 16,17 , we next tested whether these neurons mediate intergenerational heat tolerance upon maternal pheromone exposure