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[2] The decline in GHK-Cu levels correlates temporally with increased risk of neurodegenerative conditions, and the peptide's antioxidant and anti-inflammatory gene expression profile is theoretically relevant to brain aging
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Cell 18 , 884901 (2010)
"How Nature builds the pigments of life" (PDF)
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found that a substance called dehydroabietic acid binds to Keap1, activates NRF2-ARE, induces downstream gene expression, which in turn upregulates GSH, GPX4, inhibits ROS accumulation and lipid peroxidation, suppresses ferroptosis and NAFLD [148]
