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271,272 Additionally, hyperglycemia-induced oxidative and nitrosative stress activates poly(ADP-ribose) polymerase (PARP), a nuclear enzyme involved in DNA repair
Activated functions include CD8 + T lymphocyte proliferation, cellular immune responses, antigen expression, and cell death in tumor cell lines
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[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Allan NP, Yamamoto BY, Kunihiro BP, Nunokawa CKL, Rubas NC, Wells RK, Umeda L, Phankitnirundorn K, Torres A, Peres R, Takahashi E, Maunakea AK
