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PMID 11514662

Figures 1B , 3 ) is not fully ameliorated by conventional subcutaneous insulin administration, most likely because subcutaneous administration of insulin cannot fully compensate for the normal portal delivery of insulin to the liver

10.3389/fphar.2022.878724

But genetic counseling is advised to understand the risks and take precautions

Thioredoxin has also been shown to bind to ASK1 to inhibit its activity as a kinase [32]
