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The very low rate constants for direct, glutathione-independent dithiol-disulfide exchange reactions between glutaredoxins and roGFP2 or other protein(S 2 )/protein(SH) 2 couples (despite favorable thermodynamics) are a prerequisite and great advantage for reliable redox measurements in vivo

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or long-acting testosterone undecanoate / Nebido every 1014 weeks) Transdermal gels or creams applied daily to the skin Patches worn on the skin Subcutaneous pellets implanted under the skin every few months (less common in Thailand) Because you are adding testosterone from outside, your brain detects "enough testosterone" and dials down its own signal to the testes