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2018;13(2):e0192801

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The most important enriched pathways were the neuroactive ligand-receptor interaction pathway (hsa04080, P -value = 1.78E-22) and the PI3K-Akt signaling pathway (hsa04151, P -value = 7.33816E-15), which are related to human diseases and are mainly associated with Figure 9C

Propionyl-CoA is finally converted to propionyl phosphate and then to propionic acid by phosphotransacylase and propionate kinase [189,192,200]

CVB3 is included in the genus Enterovirus within the family Picornaviridae and is a major causative agent of cardiac muscle infection, but the mechanism is still unclear (61)
