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These statistical indices are applied over the predictions of the equations of state, the Arrhenius-shape model, and other empirical correlations suggested in the literature

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This forward-looking perspective underscores that energy metabolism functions not merely as a support system for neuronal activity but as a pivotal regulator in brain health and disease through mechanisms such as mitochondrial ATP synthesis, calcium buffering, and oxidative stress response (Nicholls and Budd, 2000)