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3.2.3 PINK1 PINK1 is a serine/threonine protein kinase localized in mitochondria

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Besides triggering a sequence of events that cause toxic outcomes, exposure to xenobiotics leads to induced oxidative stress, generating an over production of reactive oxygen species (ROS) [49] and consequently triggering oxidative damage to macromolecules such as proteins, lipids, and nucleic acids [50, 51]