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Overactivated fibroblasts drive abnormal fibrosis accumulation to maintain dynamic balance between inflammation and extracellular matrix (ECM) stiffness

Therefore targeting Wnt signaling upstream of TCF/-catenin is also an important therapeutic option

Drugs that promote healing and tissue regeneration often work by manipulating pathways like angiogenesis (blood vessel growth) and cell proliferation

The peptide does not stimulate the tissue growth pathways that cause joint and tendon issues

Regarding safety, the majority of reported adverse events were mild to moderate, ranging from 88% to 96%, depending on the specific study group