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It has been proposed that oxidative stress and free radicals play a crucial role in telomere shortening by altering both telomerase activity and telomere repeat binding factor 2 (TRF-2) expression levels [20]

Brain dysfunction in phenylketonuria: is phenylalanine toxicity the only possible cause

Smith, Z.R

The concern was not the compound itself, but the unregulated formulations and lack of clinical oversight

The accuracy of Hi-TOM has been previously validated 17,18
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