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Altogether, different chemotherapeutic agents may activate chemofog by inducing oxidative stress, which accelerates neuronal degeneration, inflammatory cytokine overproduction and a leak of the BBB

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The neuroprotective mechanisms may involve modulation of inflammatory responses within the central nervous system, promotion of neuronal survival, and enhancement of axonal regeneration and synaptic plasticity

10.1159/000490760 144 LiZ.ChenS.MaK.LvX.LinH.HuB.et al (2018c)

However, in the CHR-P group, Glx levels did not predict clinical or functional outcomes