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Moreover, treatment with bafilomycin A1 (a lysosomal ATPase inhibitor), ammonium chloride (which neutralizes acidic organelles such as lysosomes), or PepA-Me (a lysosomal aspartyl protease inhibitor) suppressed ferroptosis induced by erastin and RSL3 and decreased lysosomal ROS and ferroptotic cell deathassociated ROS

Additionally, CB1 receptors may modulate prostanoid synthesis via cyclooxygenase-2 (COX-2) regulation (19, 48)

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The goal is to preserve the structural integrity of peptides while enhancing their absorption and bioavailability

YS performed all the experiments