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2015;11:e1005035

Piecemeal necrosis, also referred to as interface hepatitis, is necrosis involving the layer of hepatocytes adjacent to the portal tract or limiting plate. 2 The term bridging necrosis is used when necrosis and inflammation dissect across the hepatic lobule from portal areas to central veins or to adjacent hepatic lobules and suggests a severe form of chronic hepatitis

No completed clinical trials evaluating tolerability in human subjects have been published as of 2026

Nevertheless, statistically significant associations with fasting C-peptide/glucose and differences between the levels of the targets were detected

10.1016/j.ahj.2019.10.009 Pubmed Abstract CrossRef Google Scholar View reference in article 18

CD38 has also been studied and analyzed for its involvement in various pathologies over the last 30 years, in particular it is significantly involved in the pathogenesis of hematological neoplasms (Fig