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5-Amino-1MQ works by inhibiting NNMT, an enzyme that consumes SAM (S-adenosylmethionine) and produces 1-methylnicotinamide

Many people do but if you have a digestive condition, low stomach acid or any gut absorption issue, very little of an oral supplement will actually be absorbed regardless of the dose

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Endogenous causes (medical conditions) When B12 is elevated without supplementation , it can indicate that the body is releasing stored B12 from damaged tissues, producing excess B12-binding proteins, or failing to clear B12 normally

Published research uses varying doses depending on the model and endpoint

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