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The interest traces to a 2014 Nature paper showing that knocking down NNMT in fat and liver protected mice against diet-induced obesity, glucose intolerance, and fatty liver, partly by shifting adipose NAD+ and SAM levels [4]
For others, their system may need a more regular top-up to maintain optimal levels
The lack of B12 affects the production of red blood cells, leading to reduced oxygen transport and poor muscle function
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