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doi: 10.1016/j.jare.2013.07.006

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El material con menos del 99% introduce variables desconocidas los picos de impurezas no caracterizados pueden tener su propia actividad biolgica o confundir las lecturas de los ensayos
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However, such non-specific immunosuppressive approaches have potentially harmful side effects that must be balanced with the patients overall treatment plan