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In the late seventies, Cobden et al
Quantification and Statistical Analysis All analyses were performed within the mixed model framework of JMP (ver.18.2.1, JMP Statistical Discovery)

In this assay format, the antigen presenting cells are loaded with the test protein in the absence of T cells, washed, and then autologous T cells are added back at a later time point, ensuring that the function of the test protein has no impact on the outcome of the assay
However, research is not considered conclusive

This review provides a systematic overview of the latest research advances in drug delivery strategies that penetrate the BBB, conducting an in-depth analysis of the mechanisms, advantages, and challenges of various strategies, and exploring their potential applications in the treatment of NDDs

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