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Huang L, Yu LJ, Zhang X, Fan B, Wang FZ, Dai YS, et al

- (+)-catechin hydrate - inhibition of isozymes GST M1-1 and M2-2 (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol - a coumaroflavan from Treculia africana, 26% total inhibition at 0.033 mM (2Z)-2-[(4-methoxyphenyl)carbonyl]-3-(2,3,4-trimethoxyphenyl)prop-2-enoic acid - - (2Z)-2-[(4-methylphenyl)carbonyl]-3-(2,3,4-trimethoxyphenyl)prop-2-enoic acid - - (2Z)-2-[(4-methylphenyl)carbonyl]-3-phenylprop-2-enoic acid - 8.1% inhibition at 0.02 mM (2Z)-3-(1,3-benzodioxol-5-yl)-2-[(4-methoxyphenyl)carbonyl]prop-2-enoic acid - 10% inhibition at 0.02 mM (2Z)-3-(1,3-benzodioxol-5-yl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - 9.6% inhibition at 0.02 mM (2Z)-3-(2-methylphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - 9.3% inhibition at 0.02 mM (2Z)-3-(3,4-dihydroxyphenyl)-2-[(4-methoxyphenyl)carbonyl]prop-2-enoic acid - - (2Z)-3-(3,4-dihydroxyphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - - (2Z)-3-(3-hydroxyphenyl)-2-[(4-methoxyphenyl)carbonyl]prop-2-enoic acid - 6.6% inhibition at 0.02 mM (2Z)-3-(3-hydroxyphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - 13.9% inhibition at 0.02 mM (2Z)-3-(3-methoxyphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - 19.0% inhibition at 0.02 mM (2Z)-3-(4-chlorophenyl)-2-[(4-methoxyphenyl)carbonyl]prop-2-enoic acid - 14.4% inhibition at 0.02 mM (2Z)-3-(4-chlorophenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - 14.4% inhibition at 0.02 mM (2Z)-3-(4-fluorophenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - - (2Z)-3-(4-hydroxy-3-methoxyphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - 8.8% inhibition at 0.02 mM (2Z)-3-(4-hydroxyphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - 12.5% inhibition at 0.02 mM (2Z)-3-(4-methoxyphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - - (2Z)-3-(4-methylphenyl)-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - - (2Z)-3-[4-(dimethylamino)phenyl]-2-[(4-methylphenyl)carbonyl]prop-2-enoic acid - 9.3% inhibition at 0.02 mM (4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)methanesulfonyl fluoride - - (4S,6Z,10Z,11aS)-4-ethoxy-6-(hydroxymethyl)-3-methylidene-10-propoxy-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one - a sesquiterpene lactone from Dicoma anomala collected from Namibia, 75% total inhibition at 0.033 mM (E)-2-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)ethene-1-sulfonyl fluoride - - (E)-N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)but-2-enamide - - 1,4-pentadiene-3-one - curcumin derivative 1,7-dihydroxyanthracen-9(10H)-one - a xanthone from Mammea africana, 21% total inhibition at 0.033 mM 1-(4-benzylpiperidin-1-yl)prop-2-en-1-one - 1-(4-phenylpiperidin-1-yl)prop-2-en-1-one - 1-chloro-2,4-dinitrobenzene - competitive inhibition by the substrate 1-methyl-2-[((2-nitrobenzyl)sulfonyl)]-1H-pyrrole - 44.3% inhibition at 0.1 mM 1-methyl-2-[(2-nitrobenzyl)sulfanyl]-1H-pyrrole - - 2,5-dibenzylidenecyclopentanone - curcumin derivative 2,6-dibenzylidenecyclohexanone - curcumin derivative 2-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)ethane-1-sulfonyl fluoride - - 2-(4-chlorophenyl)-6-[(fluorosulfonyl)oxy]quinoline-4-carboxylic acid - 2-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)imidazole - - 2-([(1-methyl-1H-pyrrol-2-yl)sulfonyl]methyl)-N-((1E)-[4-(trifluoromethyl)phenyl]methylene)aniline - 68.4% inhibition at 0.1 mM 2-([(1-methyl-1H-pyrrol-2-yl)sulfonyl]methyl)-N-[(1E)-(4-nitrophenyl)methylene]aniline - 90.0% inhibition at 0.1 mM 2-([(1-methyl-1H-pyrrol-2-yl)sulfonyl]methyl)-N-[(1E)-(phenyl)methylene]aniline - 30.2% inhibition at 0.1 mM 2-([(1-methyl-1H-pyrrol-2-yl)sulfonyl]methyl)-N-[(1E)-1H-pyrrol-2-ylmethylene]aniline - 36.0% inhibition at 0.1 mM 2-chloro-5-((cyanomethyl)amino)-N,N-dimethylbenzenesulfonamide - - 2-chloro-N,N-dimethyl-5 -(oxiran-2-ylmethyl) -benzenesulfonamide - - 2-chloro-N,N-dimethyl-5-(oxiran-2-yl)benzenesulfonamide - - 2-chloro-N,N-dimethyl-5-(vinylsulfonamido)-benzenesulfonamide - 2-chloro-N-(2-(N,N-dimethylsulfamoyl)-[1,1'-biphenyl]-4-yl)-acetamide - - 2-chloro-N-(3-(morpholinosulfonyl)-4-(trifluoromethyl)phenyl)-acetamide - - 2-chloro-N-(3-(N,N-dimethylsulfamoyl)-4-(trifluoromethoxy)-phenyl)acetamide - - 2-chloro-N-(3-(N,N-dimethylsulfamoyl)-4-(trifluoromethyl)-phenyl)acetamide - - 2-chloro-N-(3-(N,N-dimethylsulfamoyl)-4-iodophenyl)-acetamide - - 2-chloro-N-(4-(2-hydroxyphenyl)thiazol-2-yl)-N-((3-methylisoxazol-5-yl)methyl)acetamide - 2-chloro-N-(4-chloro-3-(morpholinosulfonyl)phenyl)acetamide - - 2-chloro-N-(4-chloro-3-(N,N-dimethylsulfamoyl)phenyl)-propanamide - - 2-chloro-N-(4-chloro-3-(N-((tetrahydrofuran-2-yl)methyl)-sulfamoyl)phenyl)acetamide - - 2-chloro-N-(4-chloro-3-(N-(2-hydroxyethyl)-N-methylsulfamoyl)phenyl)acetamide - - 2-chloro-N-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-acetamide - - 2-chloro-N-(4-chloro-3-(N-(2-methoxyethyl)-N-methylsulfamoyl)phenyl)acetamide - - 2-chloro-N-(4-chloro-3-(N-(2-methoxyethyl)sulfamoyl)phenyl)-acetamide - - 2-chloro-N-(4-chloro-3-(N-(3-methoxypropyl)-N-methylsulfamoyl)phenyl)acetamide - - 2-chloro-N-(4-chloro-3-(N-(3-methoxypropyl)sulfamoyl)phenyl)-acetamide - - 2-chloro-N-(4-chloro-3-(N-(tetrahydrofuran-3-yl)sulfamoyl)-phenyl)acetamide - - 2-chloro-N-(4-chloro-3-(N-isopropylsulfamoyl)phenyl)-acetamide - - 2-chloro-N-(4-chloro-3-(N-methylsulfamoyl)phenyl)acetamide - - 2-chloro-N-methyl-N-[(1-phenyl-1H-pyrazol-3-yl)methyl]acetamide i.e

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An involvement of SR-B1 mediated PI3K-Akt-eNOS signaling in HDL-induced cyclooxygenase 2 expression and prostacyclin production in endothelial cells

Las revisiones recientes destacan el potencial investigacional y, al mismo tiempo, la falta de ensayos clnicos bien controlados

Fasoli S, Marzotto M, Rizzotti L, Rossi F, Dellaglio F, Torriani S (2003) Bacterial composition of commercial probiotic products as evaluated by PCRDGGE analysis