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Furthermore, the expression of endothelial transcription factors within human brain organoids promotes neuronal maturation and reduces cell death ( Other studies have been based on the co-culture of human umbilical vein endothelial cells (HUVECs) with pluripotent stem cells before neural induction, which generated a vascular system formed by the HUVECs in the brain organoids, called HUVEC-BOs (Shi et al., 2020)

S1PS1PR3-RAS promotes the progression of S1PR3(hi) TAL1(+) T-cell acute lymphoblastic leukemia that can be effectively inhibited by an S1PR3 antagonist

Chen YH, Yao WZ, Geng B, et al