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Moreover, ART contains an endoperoxide bridge that reacts with intracellular iron ions, leading to additional ROS production [38]

The mechanisms underlying the association between adolescent cannabis use and risk of psychotic and cognitive symptoms later in life have been explored in various animal models using exposure to escalating doses of -9-tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis

Schnellmann RG, Kelly KJ

Clinical investigations suggest that the cerebrospinal fluid (CSF) levels of HMGB1 in patients with subarachnoid hemorrhage (SAH) demonstrate a positive correlation with proinflammatory factors, such as IL6 and TNF, and that the degree of HMGB1 elevation is closely related to the severity of the disease [353]

G Clin Med

heart rate control, cardioprotection