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The directional concordance, a measure of how directionally aligned the changes between the two readouts/groups are, is shown at the top of each heat map
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FIGURE 5 3.1 Polyphenolic metabolites Polyphenols, characterized by their polyphenolic structures, are secondary metabolites that are widely distributed in the skin, roots, leaves, and fruits of plants ( 3.1.1 Curcumin Curcumin (CUR) is a bioactive polyphenolic compound found in turmeric ( Curcuma longa L., belonging to the Zingiberaceae family), exhibiting anti-inflammatory, antioxidant, autophagy-enhancing, anti-apoptotic, and anti-fibrotic properties in DKD (6)
Alcohol consumption often depletes these vitamins, leading to fatigue, poor concentration, and a weakened immune system
