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Human umbilical cord mesenchymal stem cells in diabetes mellitus and its complications: applications and research advances

PMID: 36363994

When metabolic pathways are inhibited, cells activate autophagy to break down cellular components and release amino acids, fatty acids, and other nutrients that can be reutilized

These data suggested that the protection of 5-HT might be partially due to the inhibition of apoptosis of hepatic cells mainly by suppression of Bcl-2 proteins phosphorylation

As to the pi class, GSTP1-1 point mutations in both exon 5 (codon 105) and exon 6 (codon 114) were observed and shown to have an impact on the enzymatic activity 32

Interestingly, the level of glutathione (GSH), which is a cofactor for the antioxidant enzymes (GPX and glutathione transferase), is reduced in people suffering from anorexia