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Luckily, the risks associated with a B12 deficient diet are generally well-known in vegan and vegetarian circles

Some modified peptides can be administered nasally or dermally (via cream), but bioavailability through these routes remains inconsistent and rare

Glycocalyx-mimicking nanoparticles with differential organ selectivity for drug delivery and therapy

Its an exciting option to consider with a doctors oversight, given its good safety profile

doi: 10.1186/s12931-018-0785-0 65

Stress increases energy demands in the brain, and though vital, energy production can be a messy job, creating a lot of free radicals.[1][2] Add to this inflammation from numerous sources, and something needs to be present to counterbalance it