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Selenium combined with iodine improves the conversion of T4 to T3, a more active form of the hormone, hence facilitating the effective generation of thyroid hormone [64]

Additionally, certain nanocarriers still face payload limitations- while NLCs improved capacity over solid lipid nanoparticles, some highly bioactive nutraceuticals require even higher loading or multiple compound co-entrapment, pushing existing techniques to their limits (189193)

Several miRNAs could regulate the expression of SIRT1 in CRC, with miR-34a, miR-222-3p, and miR-132-3p being identified as regulators that can decrease its expression in CRC tissues

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1) from 3,4- cis -leucoanthocyanidins ( 2 ) to anthocyanidins ( 3 ) is thought to be catalysed by the Fe/-ketoglutarate-dependent dioxygenase leucoanthocyanidin dioxygenase (LDOX), also called anthocyanidin synthase (ANS) 8,9

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