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Injectable cyanocobalamin must be stored below 40C (104F), away from light, and protected from the freezing

Lower-dose loading schedules (100500 g/day) were also reported, particularly in less severe cases, and a few patients received intravenous high-dose B12 of 1,000 g every other day for 3 weeks

By analogy to cytoplasmic metal sensors, knowledge of the metal availabilities to which sensors are tuned (Section 6.5), should advance understanding of how metals, including Co(II), are discerned by extra-cytoplasmic proteins

Irrmischer et al., 2025

Progress on the function and application of thymosin 4

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