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Microbial influences on cardiometabolic disorders The gut microbiome has emerged as a central regulator of cardiometabolic health, exerting influence through complex interactions with host metabolism, immunity, and endocrine signaling (Tang et al., 2017)

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In the United States, more than 80% of Shigella organisms are resistant to ampicillin, and 47% are resistant to TMP-SMX.7,11 Significant resistance has not yet been found to the quinolone agents ciprofloxacin and norfloxacin, and one of these should be considered the drug of choice unless sensitivity studies demonstrate that the organism is sensitive to either ampicillin or TMP-SMX