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In contrast, patients without SURF mutations show symmetrical bilateral basal ganglia involvement without significant white matter or brainstem abnormalities (41)

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Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP

Do not use phosphate-buffered saline (PBS) at high concentrations, as phosphate can compete with the peptide for copper coordination at elevated temperatures, potentially displacing the metal