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ROCK and PDE-5 Inhibitors for the treatment of dementia: literature review and meta-analysis

Plsson-McDermott EM, ONeill LA

doi:10.1002/art.40662 Wiener RC, Shankar A

The compound has been evaluated in a phase 2 clinical trial which included adult patients with either myoclonic epilepsy, lactic acidosis, and stroke-like episodes (MELAS), Lebers hereditary optic neuropathy (LHON), or CPEO

313 S-ALI is the leading cause of poor prognosis in sepsis patients and is positively correlated with high lung lactate levels

Sepsis Sepsis, a systemic immune disease caused by infection, disrupts the inflammatory response and is closely related to serum lactate levels