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In clinical settings, intravenous choline supplementation is sometimes used for patients with critical illness, liver disease, or total parenteral nutrition (TPN) to prevent or correct deficiency-related complications

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doi: 10.1016/j.bbrc.2016.11.017 135 GengJYangCWangBZhangXHuTGuYet al

The canonical interpretation of the Warburg effect implies that cells bypass the mitochondrial respiratory chain for the synthesis of ATP even in the presence of adequate oxygen supply (Rohrig and Schulze, 2016