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doi: 10.3389/fimmu.2025.1604652 Received 02 April 2025 Accepted 23 May 2025 Published 06 June 2025 Volume 16 - 2025 Edited by Zhengyu Jiang, Second Military Medical University, China Reviewed by Feng Zhang, Nanjing University of Chinese Medicine, China Fangyang Fan, Beijing University of Chinese Medicine, China Updates Copyright 2025 Xia, Li, Shi, Sun and He

Alternatively, the response of a known second messenger system following interaction of a compound to be screened and the receptor is measured and the ability of the compound to bind to the receptor and elicit a second messenger response is measured to determine if the compound is a potential agonist or antagonist

Central elements of the system are the two redox couples ascorbate (AsA)/dehydroascorbate (DHA) and glutathione (GSH)/glutathione disulfide (GSSG)

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The role of mitochondrial dysfunction in sepsis-induced multi-organ failure

Visible improvements in hair density and thic kness are typically observed w ithin 46 months of consistent use