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Metformin: a review of its pharmacological properties and therapeutic use

These investigations contribute to broader research into aging-associated cellular mechanisms

And heres how

cyanocobalamin (vitamin b12) assist in virtually all metabolic processes, most notably the formation of red blood cells, and stimulates protein, carbohydrate and fat metabolism
Innovations in deep brain stimulation methodology
Angiogenesis: Stimulates blood vessel growth and tissue repair, including in aged animals (PubMed 15037013)