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Further studies are underway to improve the system including screening of BacD homologs with higher enzymatic activity and substrate specificity, enhancing AQ efflux using dipeptide efflux pump, reducing the degradation of alanine by blocking its catabolism, and scale-up of the bioconversion in fermenters

Lack of vitamin D receptor causes dysbiosis and changes the functions of the murine intestinal microbiome

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It has also been observed that overexpression of NRF2 promotes angiogenesis and resistance to cancer therapies, resulting in poor outcomes 63

10.1242/jcs.151068 234 SchlunkF.PfeilschifterW.YigitkanliK.LoE

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